Testing of VKORC1 and CYP2C9 alleles to guide warfarin dosingTest Category: Pharmacogenomic (Treatment)
نویسندگان
چکیده
منابع مشابه
Testing of VKORC1 and CYP2C9 alleles to guide warfarin dosing
Warfarin is an oral anticoagulant that is widely prescribed to prevent thromboembolic events in persons at increased risk. The optimal dose is difficult to establish because it can vary 10-fold among individuals due to clinical and demographic factors. Testing for variants of the vitamin K epoxide reductase complex 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) genes has been proposed for use in g...
متن کاملTesting of VKORC1 and CYP2C9 alleles to guide warfarin dosing Œ PLOS Currents Evidence on Genomic Tests
Warfarin is an oral anticoagulant that is widely prescribed to prevent thromboembolic events in persons at increased risk. The optimal dose is difficult to establish because it can vary 10-fold among individuals due to clinical and demographic factors. Testing for variants of the vitamin K epoxide reductase complex 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) genes has been proposed for use in g...
متن کاملTesting of VKORC1 and CYP2C9 alleles to guide warfarin dosing Œ PLOS Currents Evidence on Genomic Tests
Warfarin is an oral anticoagulant that is widely prescribed to prevent thromboembolic events in persons at increased risk. The optimal dose is difficult to establish because it can vary 10-fold among individuals due to clinical and demographic factors. Testing for variants of the vitamin K epoxide reductase complex 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) genes has been proposed for use in g...
متن کاملTesting of VKORC1 and CYP2C9 alleles to guide warfarin dosing Œ PLOS Currents Evidence on Genomic Tests
Warfarin is an oral anticoagulant that is widely prescribed to prevent thromboembolic events in persons at increased risk. The optimal dose is difficult to establish because it can vary 10-fold among individuals due to clinical and demographic factors. Testing for variants of the vitamin K epoxide reductase complex 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) genes has been proposed for use in g...
متن کاملPharmacogenomic testing to guide treatment using antipsychotic medications
This review evaluates the utilization of pharmacogenomic testing to guide treatment with antipsychotic medications as well as the evidence supporting the use of pharmacogenomic testing. There are two basic objectives for using pharmacogenomic testing. The first pharmacogenomic objective is to minimize adverse effects. The second pharmacogenomic objective is to improve clinical outcomes. While a...
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ژورنال
عنوان ژورنال: PLoS Currents
سال: 2010
ISSN: 2157-3999
DOI: 10.1371/currents.rrn1155